Sulfated glycosaminoglycans in human vocal fold lamina propria
نویسندگان
چکیده
منابع مشابه
Sulfated glycosaminoglycans in human vocal fold lamina propria.
INTRODUCTION The distribution, concentration and function of glycosaminoglycans in the various vocal fold tissues are still unclear. OBJECTIVE To evaluate the distribution and concentration of sulfated glycosaminoglycans in different layers of the human vocal fold according to gender and age. METHODS We used 11 vocal folds obtained from cadavers (7 men and 4 women) with no laryngeal lesion,...
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OBJECTIVE To identify characteristic patterns of maturation of the human vocal fold lamina propria as it develops into a mature structure. METHODS Histologic evaluation of sectioned true vocal folds from 34 archived larynges ages 0 to 18 years using hematoxylin-eosin, trichrome, Alcian blue pH 2.5, Weigert reticular, and Miller's elastin stain. LOCATION Pathology department at a tertiary ca...
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OBJECTIVE To analyze the distributions of collagen type I, collagen type III, and versican in the lamina propria of the human vocal fold. DESIGN Cross-sectional analysis of cadaveric vocal folds of adult human larynges. SETTING Academic tertiary referral center. SUBJECTS Larynges harvested at autopsy from 10 adult men and 10 adult women. MAIN OUTCOME MEASURES Immunohistochemical reactio...
متن کاملEstablishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria.
OBJECTIVES/HYPOTHESIS Vocal fold fibrosis represents a major disease burden. Screening of antifibrotic compounds could be facilitated by an in vitro fibrogenesis system. Limitations of existing models might be overcome by implication of the excluded volume effect. STUDY DESIGN In-vitro study. METHODS Vocal fold fibroblasts obtained from rats' lamina propria were cultured in four different s...
متن کاملA two-layer composite model of the vocal fold lamina propria for fundamental frequency regulation.
The mechanical properties of the vocal fold lamina propria, including the vocal fold cover and the vocal ligament, play an important role in regulating the fundamental frequency of human phonation. This study examines the equilibrium hyperelastic tensile deformation behavior of cover and ligament specimens isolated from excised human larynges. Ogden's hyperelastic model is used to characterize ...
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ژورنال
عنوان ژورنال: Brazilian Journal of Otorhinolaryngology
سال: 2017
ISSN: 1808-8694
DOI: 10.1016/j.bjorl.2016.05.003